COVID-19 Clinical Trials: A Primer for the Cardiovascular and Cardio-Oncology Communities.
Identifieur interne : 000954 ( 2020/Analysis ); précédent : 000953; suivant : 000955COVID-19 Clinical Trials: A Primer for the Cardiovascular and Cardio-Oncology Communities.
Auteurs : Bonnie Ky ; Douglas L. Mann [États-Unis]Source :
- JACC. Basic to translational science [ 2452-302X ] ; 2020.
Abstract
The COVID-19 pandemic has resulted in a proliferation of clinical trials that are designed to slow the spread of SARS-CoV-2, the virus that causes COVID-19. The overwhelming majority of cardiovascular and cancer patients are at increased risk for SARS-CoV-2 infection; accordingly, the cardiovascular and cardio-oncology communities are playing a major role in caring for COVID-19 patients. Many of the therapeutic agents that are being used to treat patients with COVID-19 are repurposed treatments for influenza, drugs that were not effective in Ebola patients, or treatments for malaria that were developed decades ago, and are unlikely to be familiar to the cardiovascular and cardio-oncology communities. Here we have provided a foundation for cardiovascular and cardio-oncology physicians who are on the frontline providing care to COVID-19 patients, so that they can better understand the emerging cardiovascular epidemiology of COVID-19, as well as the biological rationale for the clinical trials that are ongoing for the treatment of COVID-19 patients.
DOI: 10.1016/j.jacbts.2020.04.003
PubMed: 32309679
Affiliations:
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pubmed:32309679Le document en format XML
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Mann</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Division of Cardiology, Center for Cardiovascular Research, Washington University School of Medicine, St. Louis, MO.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Missouri (État)</region></placeName><wicri:cityArea>Department of Medicine, Division of Cardiology, Center for Cardiovascular Research, Washington University School of Medicine, St. Louis</wicri:cityArea></affiliation></author></analytic><series><title level="j">JACC. Basic to translational science</title><idno type="eISSN">2452-302X</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The COVID-19 pandemic has resulted in a proliferation of clinical trials that are designed to slow the spread of SARS-CoV-2, the virus that causes COVID-19. The overwhelming majority of cardiovascular and cancer patients are at increased risk for SARS-CoV-2 infection; accordingly, the cardiovascular and cardio-oncology communities are playing a major role in caring for COVID-19 patients. Many of the therapeutic agents that are being used to treat patients with COVID-19 are repurposed treatments for influenza, drugs that were not effective in Ebola patients, or treatments for malaria that were developed decades ago, and are unlikely to be familiar to the cardiovascular and cardio-oncology communities. Here we have provided a foundation for cardiovascular and cardio-oncology physicians who are on the frontline providing care to COVID-19 patients, so that they can better understand the emerging cardiovascular epidemiology of COVID-19, as well as the biological rationale for the clinical trials that are ongoing for the treatment of COVID-19 patients.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Missouri (État)</li></region></list><tree><noCountry><name sortKey="Ky, Bonnie" sort="Ky, Bonnie" uniqKey="Ky B" first="Bonnie" last="Ky">Bonnie Ky</name></noCountry><country name="États-Unis"><region name="Missouri (État)"><name sortKey="Mann, Douglas L" sort="Mann, Douglas L" uniqKey="Mann D" first="Douglas L" last="Mann">Douglas L. Mann</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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